Mycotoxins poisonous mushrooms

Mycotoxins are toxic substances produced by molds and fiingi, such as mushrooms. These toxic substances, known as secondary metabolites, are by-products of metabolism that are inessential to fungal growth. Although some mycotoxins can be used for medicinal purposes, most are poisonous if eaten in sufficient quantity. 

The mode of action of mushroom-produced mycotoxins varies considerably. Alpha amanitin, amatoxin produced by some species of Amanita, is a class A poison that acts by inhibiting a critical nuclear polymerase that enables the cell to make protein. Once the function of this RNA polymerase is curtailed, basic life processes cease. Attempts to kill alpha amanitin with antibodies have proven to be even more harmful to patients than the poison itself. Most forms of mushroom poisoning can be treated with rapid lavage (induced vomiting) or medically approved ingestion of charcoal to absorb the toxin before it is absorbed into the stomach. 

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