Mutual optical resolution

Toda, F., Tanaka, K., and Nagamatsu, S. (1984) Mutual Optical Resolution of 2,2 -Dihydroxy-l, 1 -binaphthyl and Alkyl Aryl or Dialkyl Sulfoxides by Complex Formation, Tetrahedron Lett., 25, 4929-4932. 

ABSTRACT. Novel optical resolutions of guest compounds by inclusion complex formation with optically active host compound are reviewed Tertiary acetylenic alcohols, cyanohydrins, and secondary alcohols were resolved by complexation with alkaloids such as brucine or sparteine. Cycloalkanones, 2,3 -epoxycyclohexanones, and some other neutral compounds were resolved by complex formation with optically active diacetylenic diol. Mutual optical resolution of bis-g-naphthol and sulfoxides by complex formation was also reviewed. 

Mutual Optical Resolution of Tertiary Acetylenic Alcohols and Sparteine by Complex Formation... 

MUTUAL OPTICAL RESOLUTION OF BIS-g-NAPHTHOL AND ALKYL ARYL OR DIALKYL SULFOXIDES BY COMPLEX FORMATION... 

If host and guest molecules mutually recognize their chiralities at inclusion formation, the process could be used for optical resolution. In other words, when the host compound is optically active, one enantiomer of the guest compound should be included selectively. In turn, if an optical active guest molecule forms a crystal inclusion with one enantiomer of the host compound selectively, the host compound yields resolved. This section deals with the resolution via inclusion formation using host compounds such as alkaloids, 2-propyn-l-ols, 2,4-hexadiyne-l,6-diols, 2,2 -dihydroxy-l,r-binaphthol (7), and 2,2 -dihydroxy-9,9 -spirobifluorene (10a). 

Fig. 8.3. Ultrashort optical pulses can be shaped by adjusting the phase and amplitude of each spectral component [27]. In the device, the input pulse is incident on a grating that disperses the different colors in different directions, as shown in the figure. The colors are collimated and focused by a lens or mirror. A second similar arrangement in reverse reconstitutes the pulse by redirecting the colors to another grating. At the mutual focal plane of the two lenses, the spectrum of the input pulse is completely resolved so that each spatial location corresponds to a single frequency (or a narrow band). By inserting at this plane a material that causes variations in the phase of each resolved frequency, one can construct a pulse of arbitrary shape, constrained only by the spatial resolution of the arrangement.

---