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Mutations large gene

Scanning Is Helpful for Large Gene Mutation Characterization. 209... [Pg.171]

The protein truncation test is a way of testing large genes (e.g., NEl) for which an antibody is available. PTT can detect nonsense mutations that are peptide chain terminating. These show up, after reverse transcription/cell-free translation, as shorter-than-normal peptides in an electrophoretic gel (Eig. 3C). [Pg.221]

Mutations are modifications of genetic information. The natural spontaneous mutation rate in humans is approx. 10 mutations per gene. Because of the extremely large number of genes, a mutation is not a rare event in humans. [Pg.29]

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See also in sourсe #XX -- [ Pg.209 ]



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