Muscle pain

Most of the time, the powerful analgesia suppHed by morphine and the other opioid analgesics is not needed. Rather, a mild analgesic, such as aspirin, the most commonly employed analgesic agent, can be used for the treatment of simple pain associated with headaches, minor muscle pain, mild trauma, arthritis, cold and flu symptoms, and fever. 

The most significant occupational exposures to zinc would occur during the smelting and refining of zinc ore. The standards for occupational exposure have been estabUshed at a level to prevent the onset of metal fume fever. This temporary condition is caused by excessive exposure to freshly formed fumes of zinc oxide and results in flulike symptoms of fever, chills, headache, muscle pain, nausea and vomiting. 

Signs and symptoms resembling serum sickness-chills, fever, edema, joint and muscle pain, and malaise... 

Administration of naltrexone may result in anxiety, dif-ficully sleeping, abdominal cramps, nasal congestion, joint and muscle pain, nausea, vomiting, dizziness, irritability, depression, fatigue, and drowsiness. 

HMG-CoA REDUCTASE INHIBITORS AND FlBRIC ACID DERIVATIVES. The antihyperlipidemic drugp, particularly die HMG-CoA reductase inhibitors, have been associated with skeletal muscle effects leading to rhab-domyolysis. Rhabdomyolysis is a very rare condition in which muscle damage results in die release of muscle cell contents into die bloodstream. Rhabdomyolysis may precipitate renal dysfunction or acute renal failure The nurse is alert for unexplained muscle pain, muscle tenderness, or weakness, especially if tiiey are accompanied by malaise or fever. These symptoms should be reported to die primary health care provider because the drug may be discontinued. 

Contact the primary healdi care provider as soon as possible if nausea vomiting muscle pain, tenderness, or weakness fever upper respiratory infection rash itching or extreme fatigue occurs. 

Warning sgns of a fluid and electrolyte imbalance include dry mouth, thirst, weakness lethargy, drowsiness restlessness muscle pains or cramps confuson, gastrointestinal disturbances hypotenson, oliguria, tachycardia, and seizures... 

Ovarian enlargement, hemoperitoneum, febrile reactions, multiple pregnancies, hypersensitivity Failure to respond to therapy due to development of antibodies, hypothyroidism, insulin resistance, swelling of the joints, joint and/or muscle pain Same as somatropin... 

These hormones cause few adverse reactions when administered as directed. Antibodies to somatropin may develop in a small number of patients, resulting in a failure to experience response to therapy, namely, failure of the drug to produce growth in the child. Some patients may experience hypothyroidism or insulin resistance Swelling, joint pain, and muscle pain may also occur. 

Hypothyroid myopathy occurs in about 30% of patients with hypothyroidism irrespective of its cause. Muscle pain, cramps, and stiffness may be seen, and are often exacerbated by cold weather. Pseudomyotonic features of delayed muscle contraction and relaxation are common. Myoedema (the mounding phenomenon) is due to the painless, electrically silent contracture produced on direct percussion. Muscle biopsy often shows a predominance of type 1 (slow-twitch) fibers, again analogous to that seen in experimental hypothyroidism (Figure 22). Muscle hypertrophy with weakness and slowness of movement occurs in the Debre-Semelaigne syndrome seen in severely hypothyroid children, and Hoffman s syndrome is a similar condition seen in adults with hypothyroidism, but is also accompanied by painful spasms. 

Using a within-subject, placebo-controlled design, Haney et al. (2003) recently reported that nefazodone, an antidepressant that also has some sedative properties, decreased reports of anxiety and muscle pain during closely mon-... 

Baseline CK should be obtained in all patients prior to starting statin therapy. Follow-up CK should only be obtained in patients complaining of muscle pain, weakness, tenderness, or brown urine. Routine monitoring of CK is of little value in the absence of clinical signs or symptoms. Patient assessment for symptoms of myopathy should be done 6 to 12 weeks after starting therapy... 

Typical symptoms associated with stage 5 CKD include pruritus, dysgeusia, nausea, vomiting, constipation, muscle pain, fatigue, and bleeding abnormalities. 

Chills, diaphoresis, headache, anorexia, cough, weakness, sore throat, dizziness, and muscle pains are frequently present before the onset of fever. 

Malaria is transmitted by the bites of the Anopheles mosquitoes which introduce into the bloodstream one of four species of sporozoites of the plasmodia (Plasmodium falciparum, P. ovale, P. vivax or P. malariae). Initial symptoms of malaria are nonspecific and may resemble influenza and include chills, headache, fatigue, muscle pain, rigors, and nausea. The onset of the symptoms is between 1 to 3 weeks following exposure. Fever may appear 2 to 3 days after initial symptoms and may follow a pattern and occur every 2 or 3 days (P. vivax, P. ovale and P. malariae). Fever with P. falciparum can be erratic and may not follow specific patterns. It is not unusual for patients to have concomitant infections with P. vivax and P. falciparum. Falciparum malaria must always be regarded as a life-threatening medical emergency. 

In Asia, this plant is valued as a remedy for fever, rheumatism, gout, and inflammatory illnesses. In China, the roots are used as febrifuges, deobstruents, and carminatives, and are used to assuage muscle pains, thoracic and abdominal inflammations, puerperal fever, and diarrhea. 

The amino acid precursor for 5-HT, L-tryptophan, increases the biosynthesis 5-HT and, therefore, has been investigated for potential antidepressant properties, but with mixed results (Green and Costain, 1979). It was withdrawn in 1990, following a number of fatal cases of eosinophilia myalgia (a disorder characterised by severe muscle pain and abnormally high levels of one type of white blood cell, the eosinophil) in individuals principally using it as a natural hypnotic. 

The answer is a. (Hardman, pp 885-8870 Lovastatin should not be used in patients with severe liver disease. With routine use of lovastatin, serum transaminase values may rise, and in such patients the drug may be continued only with great caution. Lovastatin has also been associated with lenticular opacities, and slit-lamp studies should be done before and one year after the start of therapy There is no effect on the otic nerve. The drug is not toxic to the renal system, and reports of bone marrow depression are very rare There is a small incidence of myopathy, and levels of creatinine kinase should be measured when unexplained muscle pain occurs. Combination with cyclosporine or clofibrate has led to myopathy There is no danger in use with bile acid sequestrants. 

Case reports are available regarding lethal effects of acute exposure to arsine (Pinto et al. 1950 Morse and Setterlind 1950 Hesdorffer et al. 1986). However, no definitive quantitative exposure data accompany these reports. Signs and symptoms varied depending on the exposure situation but usually included abdominal and muscle pain, nausea and diarrhea, hematuria, and oliguria. Delayed lethality, common in arsine poisoning, varied considerably. 

Signs and Symptoms Are nonspecific and consist of irregular fever, headache, profound weakness and fatigue, chills and sweating, generalized severe joint and muscle pain (myalgia), anorexia, weight loss, and depression. Joint complications are common. 

Signs and Symptoms Diagnosis of psittacosis can be difficult. There is a variable clinical presentation but may include fever, headache, muscle pain (myalgia), chills and upper or lower respiratory tract disease, and dry cough. Pneumonia is often evident in chest x-rays. 

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