Multivalent ligation

Keywords Carbohydrate-lectin interaction, Chemoselective ligation, Conjugation technique, Glycocluster, Glycoconjugate, Glycodendrimer, Multivalency... [Pg.17]

Many classical reactions have been used to link a carbohydrate epitope to multivalent scaffolds. During recent years chemoselective ligation [171,172] and click chemistry have become popular. The term chemoselective ligation is used for reactions which allow selective bond-formation of two complementary functional groups in the presence of other, non-complementary functional groups under particularly bioorthogonal conditions [173], Amide bond formation is possibly the... [Pg.41]

A. Dirksen, E.W. Meijer, W. Adriaens, T.M. Hackeng, Strategy for the synthesis of multivalent peptide-based nonsymmetric dendrimers by native chemical ligation, Chem. Commun. 2006, 15, 1667. [Pg.590]

C Synthesis of a Multivalent Glycocyclopeptide using Oxime Ligation... [Pg.39]

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