Multiple myeloma epidemiology

Cancer. There is no specific evidence from epidemiological studies that diazinon causes cancer in humans. Several studies have reported an increased incidence of cancers (brain tumors, Hodgkin s lymphoma, multiple myelomas) in humans who were concurrently or sequentially exposed to a number of insecticides, including diazinon (Cantor et al. 1992 Davis et al. 1993 Morris et al. 1986). However, it is not possible to attribute the increase in cancer incidence exclusively to diazinon exposure. Consequently, while the findings in these studies suggest an elevated risk for the cancers from high exposure to insecticides, in general, the data are far too limited to be used to evaluate the potential for diazinon to cause cancer in humans. 

Lim, U., Weinstein, S., Albanes, D., Pietinen, P., Teerenhovi, L., Taylor, P.R., Virtamo, J., and Stolzenberg-Solomon, R., 2006. Dietary factors of one-carbon metaboKsm in relation to non-Hodgkin lymphoma and multiple myeloma in a cohort of male smokers. Cancer Epidemiology, Biomarkers Prevention. 15 1109 1114. 

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