Multielemental quantification

Neutron activation analysis (NAA) is also a multielemental quantification technique which can simultaneously measure more than 30 elements in a sample. The detection limits of NAA range from 10 to 10 gg dependent upon the irradiation parameters, measurement eonditions, and nuclear parameters of the elements of interest. It has been mueh used in many areas of fundamental and applied researeh as well as industrial applieations. The theme... 

In general, ICP-MS and NAA are excellent techniques for multielemental quantification. NAA can achieve non-destructive and in situ multielemental analysis for solid samples while ICP-MS needs laser ablation for this purpose. 

The sputtering yield S can be measured from elemental and multielemental standards under various operational conditions and can therefore be known to reasonable accuracy for the material being analyzed by judicious interptolation between standards. However, the ionization probability a cannot be measured easily, and attempting to measure it for a set of standards and then trying to interpolate would be of no use, because it is very matrix and concentration dependent and can vary very rapidly. In fact, it represents the principal obstacle in achieving proper quantification in SSIMS. 

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