Multicenter trials interactions

Kleiman NS, Lincoff AM, Kereiakes DJ, et al, Diabetes mellitus, glycoprotein llb/llla blockade, and heparin evidence for a complex interaction in a multicenter trial, EPILOG Investigators. Circulation 1998 97(1 9) 1912-1 920. [Pg.480]

Reviews of ranitidine continue to substantiate its clinical efficacy and selectivity of action. " A multicenter trial in America has been assessed. Drug interactions, pharmacodynamics and pharmacokinetics of ranitidine and clmetldine have been compared. ... [Pg.81]

Chuang-Stein C, Tong DM (1996) The impact of parametrization on the interpretation of the main-effect terms in the presence of an interaction. Drug Information Journal 30 421-424. Dragalin V, Fedorov V, Jones B, Rockhold F (2001) Estimation of the combined response to treatment in multicenter trials. Journal of Biopharmaceutical Statistics 11 275-295. [Pg.230]

Adams C, Totpal K, Lawrence D, Marsters S, Pitti R, Yee S, Ross S, Deforge L, Koeppen H, Sagolla M, Compaan D, Lowman H, Hymowitz S, Ashkenazi A (2008) Structural and functional analysis of the interaction between the agonistic monoclonal antibody Apomab and the proapoptotic receptor DR5. Cell Death Differ 15 751-761 Allan NC, Richards SM, Shepherd PC (1995) UK Medical Research Council randomized, multicenter trial of interferon alfa nl for chronic myeloid leukaemia improved survival irrespective of cytogenetic response. Lancet 345 1392-1397... [Pg.141]

Ciccone A, Motto C, Aritzu E, Piana A, Candelise L. Negative interaction of aspirin and streptokinase in acute ischemic stroke further analysis of the Multicenter Acute Stroke Trial—Italy. Cerebrovasc Dis 2000 10(l) 61-4. [Pg.29]

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