Mukaiyama-Michael reactions 2- trimethylsilyloxyfuran

In the Mukaiyama-Michael reaction of 3-acryloyl- or 3-crotonoyloxazolidinone with 2-trimethylsilyloxyfuran, the scandium-(4 S,5 S)-4-CH20TIPS-5-Ph-pybox... 

G. Desimoni, G. Faita, S. Fflippone, M. MeUa, M.G. Zampori, M. Zema, A new and highly efficient catalyst for the enantioselective Mukaiyama-Michael reaction between (E)-3-crotonoyl-l,3-oxazolidin-2-one and 2-trimethylsilyloxyfuran, Tetrahedron 57 (2001) 10203-10212. 

Vinylogous Mukaiyama-Michael additions of 2-trimethylsilyloxyfuran to 3-alkenoyl-2-oxazolidinones to provide 7-butenolides were shown to be /7-selective. The reaction could be rendered enantioselective in the presence of a (T symmetric copper-bisoxazoline complex <1997T17015, 1997SL568> or a l,T-binaphthyl-2,2 -diamine-nickel(ii) complex as catalyst, as depicted in Equation (16) <2004CC1414>. 

Michael addition/enamine chlorination reaction <05JA15051>. 2-Trimethylsilyloxyfuran reacted readily with chiral tungsten carbene complexes in a Mukaiyama-Michael addition manner to give the anti products selectively, as depicted in the example below <05AGa)6583>. 

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