Mucus glycoproteins subunits

Fig. 3.3. Schematic illustration of the proposed architecture of mucus glycoproteins, (a) Subunits constitute a linear array of oligosaccharide clusters interspersed with naked stretches of protein. (b) Trypsin digestion affords glycopeptides corresponding to the oligosaccharide clusters. (c) The whole mucins are formed by an end-to-end association of subunits via disulphide bonds, (d) The hydrodynamic model of mucus glycoproteins conforms to a random coil within a spheroidal solvent domain. (After Allen et al., 1984.)...

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