MT and Tolerance to Ionizing Radiation

Cultured mammalian cells that overexpress MT are unusually resistant to X-ray damage (Bakka and Webb 1981), and this has led some investigators to propose that MTs may function as scavengers for free radicals (Thornalley and Vasak 1985). Glutathione, 

Likewise, Morcillo etal. (2000) have suggested that an enhanced lipid peroxidation is not a prerequisite for the induction of hepatic MT synthesis after yirradiation. 

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