MS analysis after photolysis

Weber and Beck-Sickinger reported a study on the photochemical behavior of different photophores [86]. For this, the synthetic pentapeptide thymopentin, or TP5 (Arg-Lys-Asp-Val-Thr) was modified with each of the photocrosslinkers (C-terminal Tyr was replaced by Phe(Tmd), and Bpa or 4-azidobenzoic acid was coupled to the N-terminus), thereby obtaining three different photoreactive peptides. The conversion and product formation were followed by LC-MS analysis after photolysis in water, n-propanol. and a water/n-propanol mixture (1 1, v/v). It was found that both the diazirine and aryl azide were quickly converted into a... 

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See also in sourсe #XX -- [ , , ]

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