Mouth Glucocorticoids, inhaled

To ensure optimal drug delivery, it is necessary to coordinate activation of the inhaler with inspiration and a final hold of breath. Many patients, especially the young and the elderly, find this very difficult and spacer devices are often used between the inhaler and lips these act as an aerosol reservoir and also reduce impaction of aerosol in the oropharynx. Topical deposition can cause local side effects in the mouth, particularly Candida with inhaled glucocorticoids a spacer abolishes this problem. 

Inhaled glucocorticoids are generally safe at low doses. Topical effects (oral Candida and hoarseness) are easily eliminated by using a spacer device and rinsing the mouth. High doses (> 1500 microgram... 

General anesthetics, see Anesthetics Germanium, 16.545 Glucocorticoids bone, 16.447, 22.182, 25.195 contact allergy, 15.139, 21.158 effective dose and therapeutic ratio, 23.175 and eyes, 29.481 and growth, 14.335 inhaled, children, risks in, 27.174 inhaled, effects on mouth and throat, 29.168... 

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