Most of Side Effects

The new targets of this example are the caspases. i While this is indeed a real example, maintaining confidentiality precludes us from giving all details. 

This is a partial account of what happened. At the time of this story, not all the caspases were known. People were looking at both caspase-A and caspase-B, where A B are numbers from 1 to 10. One group of investigators had an inhibitor [ 1] for caspase-A, but. 

Tkble 18.1 Inhibiting Cell Death by Inhibiting Caspases 

12 Caspases are a family of intracellular cysteine endopeptidases. They play a key role in inflammation and mammalian apoptosis. They are divided into two classes based on the lengths of their N-terminal prodomains. Caspases-1,-2,-4,-5,-8, and -10 have long prodomains and -3,-6,-7,-9 have short prodomains, [from Medical Dictionary Online] 

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