Most Challenging Molecule to Synthesize Colchicine

Summary of Calculations for Plans Involving Auxiliary Materials That Need to Be Synthesized in Addition to Target Compound 

Plan Synthesis Tree of Step in Step of Auxiliary Target Compound Compound Material Making Auxiliary Compound 

FIGURE 11.34 Starting materials used in various plans to make ibuprofen, warfarin, and (+)-paroxetine. 

---