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Morpholinoalkyl esters

Morpholinoalkyl esters (see Figure 16.1 for chemical structures) ofthe potent nonsteroidal anti-inLammatory agent, diclofenac, were prepared and characterized regarding solubility and hydrolysis reaction rates (Tammara et al., 1994). The alkyl group provides a spacer between the carboxylic acid... [Pg.440]

FIGURE 16.1 Chemical structure of water-soluble morpholinoalkyl ester prodrugs of diclofenac. The subscript equals 2, 3, or 4. [Pg.440]

Tammara, V. K., M. M. Narurkar, A. M. Crider, and M. A. Khan. 1994. Morpholinoalkyl ester prodrugs of diclofenac synthesis vitro andin vivoevaluationJ. Pharm. Sci83 644-648. [Pg.466]

Tammara, V.K. Narurkar, M.M. Crider, A.M. Khan, M.A. Morpholinoalkyl ester prodrugs of diclofenac Synthesis, in vitro and in vivo evaluation. J.Pharm.Sci., 1994, 83, 644-648 [rat plasma mefenamic acid (IS)]... [Pg.499]

Benzilic and other esters of tropine and 4-tropine a-phenylvalerie, diphenylacetic, fluorene-9-earboxylie, tropic, and other esters of /3-diethylaminoethanol tropic and other "esters of y-diethyl-amino- /3-dimethylpropanol (Fromherz esters of morpholinoalkyl alcohols. ... [Pg.112]

See other pages where Morpholinoalkyl esters is mentioned: [Pg.450]    [Pg.538]    [Pg.155]    [Pg.130]    [Pg.450]    [Pg.538]    [Pg.155]    [Pg.130]   
See also in sourсe #XX -- [ Pg.440 ]



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