Monosaccharides deuterated

Deliberate partial trimethylsilylation may be used as a means of distinguishing between various monosaccharides,199 and the nature of minor components formed on trimethylsilylation has been studied by mass spectrometry. Trimethylsilylation has been used in the separation of deuterated monosaccharides,200-203 and such deuterated trimethylsilyl derivatives as penta-0-(trimethyl-dliquid chromatography and mass spectrometry.143... 

Gas chromatographic analysis allows the determination of the monosaccharides present by comparing the retention times with those of reference compounds. It is noteworthy to mention that the chromatographic profile is quite simple, because the deuterated compounds are not separated from the non-deuterated, even if a small difference in retention time can be evidenced by comparison of specific ion chromatograms. Each monosaccharide can give a maximum of four peaks, corresponding to the cd(3 and the pyran/furan isomers. 

Reuben J (1984) Isotopic multiplets in the carbon-13 NMR spectra of polyols with partially deuterated hydroxyls. Fingerprints of molecular structure and hydrogen bonding effects in the 13C NMR spectra of monosaccharides with partially deuterated hydroxyls. J Am Chem Soc 106 6180-6186... 

Fig. 4 (a) IRID spectrum of the singly hydrated complex aMan-O-Ph. The stretching bands of the deuterated water molecule are well separated from those of the monosaccharide, (b) Preferred conformations of isolated and micro-hydrated of the p (top) and a (bottom) anomers of Man-O-Ph... 

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