Monolayers of Macromolecules at Water Surface

It is already obvious that monolayers on water are only stable if the hydrophobic part of the molecule is of right magnitude as compared to the polar part. Many macromolecules (such as proteins) form 

Stable monolayers at water surface, if the HLB is of the right balance. Especially, almost all proteins (hemoglobin, ovalbumin, bovine serum albumin, lactoglobulin, etc.) are reported to form stable monolayers at the water surface (Birdi and Fasman, 1973 Birdi, 1999). 

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