Monobenzyl-3-thienylmalonate

A mixture of monobenzyl-3-thienylmalonate (1.38 g, 5 mmol) and thionyl chloride (2.5 ml) was warmed at 50°C to 55°C for 1 hour, then at 60°C to 65°C for 10 minutes. The excess of thionyl chloride was removed in vacuo at not more than 30°C, the last traces being removed by codistillation with dry benzene (1 ml) under high vacuum, leaving monobenzyl-3-thienylmalonyl chloride as a yellow oil. 

C7H 04S 21080-92-2) see Ticarcillin 3-thienylmalonic acid monobenzyl ester monochloride (C14H11CIO3S 50893-38-4) see Temocillin 3-thienylmalonic acid monophenyl ester monochloride (CnH.jC10,S 59/18-37-5) see Temocillin... 

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