Big Chemical Encyclopedia

Chemical substances, components, reactions, process design ...

Articles Figures Tables About

Mono- 3-0-tosyl -a-CD

Dissolve 4 g a-cyclodextrin in 5 mL water. Adjust the pH value to 12 by NaOH solution. And mix with 1.4 g p-TsCl. Vigorously stir the mixture at room temperature for 5 min. The pH value would decline to 6.5. Filter the reaction solution, and separate the products by reversed-phase column. Three kinds of purified products would be detected. Mass spectrometry and NMR data showed that the three kinds of products were C-3, C-2 and C-6 position substituted toluene sulfonyl of-CDs [ 14]. [Pg.142]

5 g jS-naphthalene chloride into 50 mL 30% acetonitrile aqueous solution (pH = 12) which contains 3.5 g (i-CD. Vigorously stir the reaction buffer till the pH value reaches 7.0. Then filter the solution by reverse phase column. The product yield is about 20% [15]. [Pg.142]

Dissolve 25 g of dried fi-CD in 750 mL evaporated pyridine in ice bath. Then add the prepared solution into 70 mL benzoyl chloride solution which contains 2.4 g and dried for 20 min. Stir the reaction mixture at room temperature for 5 h. After that, stop the reaction by adding a little water. Then steam at 40°-50°C to remove pyridine. Extract the residue successively with acetone and methanol and wait for them to precipitate as white solid powder at room temperature. The white crude [Pg.142]


See other pages where Mono- 3-0-tosyl -a-CD is mentioned: [Pg.142]   


SEARCH



A-Tosylations

© 2024 chempedia.info