Molecular wires, cytochromes

Keywords Molecular Wires Cytochromes P450 Nitric Oxide Synthase ... 

Fig. 2 Molecular wires that bind cytochrome P450CAM...

Gray HB, Stout CD, Goodin DB. Conformational states of cytochrome P450cam revealed by trapping of synthetic molecular wires. J. Mol. Biol. 2004 344 455-469. 

Figure 40 Molecular surface of the substrate channel of a cytochrome F-450 protein. The surface is color coded according to the lipophilic potential (blue = almost hydrophilic, brown = almost lipophilic). The left figure shows the complete channel surface as solid model. The atoms forming the channel are represented as wire frame. The small barrel and the small cone are so-called space buttons used for the implementation of interactivity. The barrel leads to a HTML document giving a short description of the scene. By clicking on the cone the quality of the surface is reduced to chicken-wire representation. Also the color ramp, here called space ramp , is linked to other VRML files. The result of a click to the hydrophilic part is shown on the right. All parts of the surface remaining under a defined threshold of lipophilicity are removed...

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