Molecular model building automatic

This paper describes the first application of analogy and intelligence to molecular model building. It represents a departure from previous methods, a new approach aimed at rapid, automatic, accurate molecular model building. 

A refinement at atomic resolution will typically be started from a mostly complete model originating, for exan5>le, from a previous structure determination of the same molecule at lower resolution or from a model created by automatic building software using an experimental or molecular replacement based phase set. Such a model will usually describe the atoms in the stmcture with fully occupied sites and isotropic B-values. 

---