Modified chromatographic exponential

Shuangdan Chinese medicine components [Borate], [phosphate], [SDS], [ACN] Modified chromatographic exponential function (R, and T) Genetic algorithm experimental designs, RSM, MLR Precision, linearity, recovery (39)... 

Similarly, Yu et al. required a separation of the active components in Shuangdan, a Chinese medicine, to have good resolution and minimum total analysis time (39). The researchers utilized a modified chromatographic exponential function MCEF) ... 

Jeansonne, M. S. Foley, J. P. Review of the exponentially modified Gaussian chromatographic peak model since 1983,/. Chromatogr. Sci, 1991, 29, 258-266. 

For example, a Gaussian peak model is used to derive many fluently used fundamental equations in chromatography (17), but the Gaussian function rarely provides an accurate model for real chromatographic peaks. Convectional effects introduced by the flow cell can cause asymmetry in chromatographic peaks even if a Gaussian profile has been established prior to detection (18). One model diat is well accepted to represent a real chromato phic peak is an exponentially modified Gaussian (EMG) function. The FIA profile is characterized primarily by a dispersion coefficient (19) which offers information about die manifold, but direct information about the peak parameters such as second moment or variance can not be readily obtained. Recently, the EMG was used to describe FIA profiles to obtain the second moment and characterize the peak (20-22). 

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