Miscellaneous Coupling Reactions

Stereo and regiodefined alkenylmetals containing A1 or Zr react with aryl and alkenyl iodides and bromides in the presence of catalytic amounts of Ni complexes containing phosphine ligands such as PPhj, to give the corresponding coupling products [81-84]. 

Benzylic chlorides incorporated with heteroaromatic rings can also be used for such reaction [85]. 

Aryl iodides couple with aryl aldehydes in the presence of NiBr2(dppe) and Zn to give the corresponding biaryl ketones. The use of a bidentate ligand is critical to the success of this catalytic reaction [86]. 

Aryl chlorides are converted to the corresponding anilines using catalytic amounts of Ni(COD)2, dppf. and NaOBu. Electron-rich or -poor aryl chrodies as well as chloropyridine derivatives can be combined with primary and secondary amines to give the desired aryl amins in moderate to excellent yields. NiCl2(dppf) or NiCl2(phen) can also be used in place of air-sensitive Ni(COD)2 catalyst [87]. 

Arylacetic ethyl esters are prepared from arylzinc chlorides and ethyl bromoace-tate with a catalytic amount of Ni(acac)2 and a phosphine ligand at -5 °C [88], 

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Miscellaneous coupling reactions. Heck reaction and subsequent intramolecular Michael reaction are probably involved in the aminoarylation of 3-cyclohexenones/ ... 

Miscellaneous coupling reactions 404 (THF)2 with small inorganic molecules ... 

Miscellaneous Coupling Reactions of Aryl Halides with N-Nucleophiles. 188... 

Cross-Coupling Reactions of Allenes Producing Compounds with an Intact 1,2-Diene Moiety 849 Cross-Coupling Reactions of Allenyl Halides 849 Cross-Coupling Reactions of Allenylmetal Compounds 856 Cross-Coupling Reactions of a-Substituted Allenes 860 Cross-Coupling Reactions of Allenes at the Central Position 862 Synthesis of Alkynes 870 Miscellaneous Reactions 872 Conclusion 873... 

Other miscellaneous syntheses that have benefited from the introduction of dppf to the catalytic mixture include the coupling reactions of aryl triflates or halides with ketene trimethylsilyl acetals [165], The catalyst mixture is [Pd(OAc)(i -C4H7)]2/LiOAc/phos-phine. In this case, nucleophilic activation of the Si-O bond of the acetal enables an Si-Pd transmetalation to give a a-complex 52 without necessitating a phosphine... 

Pinacoiic coupling reactions 1.9233 Acyl anion and acyl radical chemistry 1.92.3.6 Miscellaneous... 

Cross-coupling reactions of miscellaneous arylmetalllc Mn, Ti, In, and Ge reagents with aryl halides and sulfonates... 

Homo-coupling reactions of miscellaneous arylmetallic reagents to biaryls... 

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