Microreactor nine-channel

The fluorination of ethyl acetoacetate can be operated in a nine-channel microreactor device for many months (Figure 8.3). Scale-out to 30 channels can be also achieved by simply exchanging a nine-channel plate for 18channel plates with no appreciable change in overall yield and conversion. 

Figure 8.3 Schematic diagram of nine-channel microreactor.

Table8.2 Directed fluorinationsofvarious 1,3-keto esters and 1,3-diketo esters in formic acid using a nine-channel microreactor. 

Figure 9.40 Fluorinations of m-benzaldehydes using a nine-channel microreactor, where —X is — NO2, —CN, CF3, or —CHO functional group. Source Reprinted with permission from Ref [121]. Copyright (2009) American Chemical Society.

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See also in sourсe #XX -- [ ]

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