Micromonospora olivoasterospora

Preparation by fermentation of Micromonospora olivoasterospora FERM-P1560 (identical with Micromonospora sp. MK-70 ATCC 31009 and ATCC 31010) and isolation/purification on ion-exchanger and column chromatography. 

New antibiotics reported this year have included several groups of closely related pseudo disaccharides fortimicin C, a carbamoyl derivative of fortimicin A (1), fortimicin D, the 6 -demethylated analogue of fortimicin A, and fortimicin KE, the d -demethylated derivative of fortimicin B (2), have been isolated from the culture broth of Micromonospora olivoasterospora, which also yields fortimicin A and and sporaricin A (3, = NHjCHaCO-) and sporaricin B (3, = H)... 

Aminocyclitol antibiotic. Prod, by Micromonospora olivoasterospora. Weakly active against gram-positive and -negative bacteria. Powder. Sol. HjO. Mp 167-169°. Mg +89 (c, 0.46 in H2O). Intermediate in the biosynthesis of Fortimicin A, F-26. 

C15H27N3O5 329.395 Aminocyclitol antibiotic. Isol. from Micromonospora olivoasterospora. Active against gram-positive and -negative bacteria. Sol. H2O. 

C14H29N3O6 335.4 Aminoglycoside antibiotic. Prod, by Micromonospora olivoasterospora. Sol. H2O. 

C15H32N4O5 348.442 Aminocyclitol antibiotic. Minor prod, isol. from Micromonospora olivoasterospora. Weakly active against grampositive and -negative bacteria. Powder. Sol. H2O. [a]o +88 (c, 1 in MeOH). Hydrochloride (1 4) [71629-36-2]... 

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