Microcosmus sulcatus

FIGURE 2t New glucosylceramides mixture (72) from the tunicate Microcosmus sulcatus. 

Acidic forms of human cerebroside sulphatase have been partially purified from invertebrates Tethya aurantium (Porifera), Patella vulgata (mollusca), Maja squinado (Arthropoda), Martlasterias glacialis (Echinodermata), and Microcosmus sulcatus (Tunicata). Enzyme preparations thus obtained cleaved cerebroside sulphates only in the presence of either specific detergents, e.g. taurodeoxycholate, or an activator protein isolated from human liver. On a molar basis, less of the activator protein was required to achieve the same activation as detergent. 

Aiello, A., Fattorusso, E., Mangoni, A., and Menna, M. (2002) Sulcaceramide, a novel triglycolsyl-ceramide from the marine ascidian Microcosmus sulcatus. Eur. J. Org. Chem., 1047-1050. 

Langer, M., Giebing, T, and D Haese, J. (1998) Purification and fimctional characterization of an 85-kDa gelsolin from the ascidians Microcosmus sulcatus and Phallusia mammilata. Comp. Biochem. Physiol., 119B, 697-704. 

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