Microchip-type laser

Besides having the rapid and global methods described above for optimization before the crystal growth process, attempts have been made at a more predictive approach (Auzel 1979) which should be useful for the materials research of compact lasers of the stoichiometric minilaser type (Danielmeyer and Weber 1972) (see sect. 6), or of the microchip type (Zayhowski and Mooradian 1989). 

The technique of isoelectric focusing has proven to be a useful tool in protein chemistry, and this too has been adapted to the microchip. Using 7-cm-long channels in glass microchips (200 [Xm wide and 10p,m deep) mixtures of Cy5-labeled peptides can be focused in less than 30 seconds. This same procedure has also been applied to plastic microchips made from EMMA by laser ablation and shown to focus mixtures of peptides labeled with rhodaraine green. Results for this type of microchannel isoelectric focusing are available in less than 5 minutes compared with traditional techniques that take over 1 hour. 

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