Michael Addition of a,P-Unsaturated N-Acylpyrrolidines

Tandem Cross-Metathesis/Hydrogenation Route to Lactones 

Ru-catalyzed cross-metathesis, hydrogenation, and subsequent ring closure has been successfully combined into a one-pot tandem process for lactone synthesis. Importantly, compatibility between the catalytic systems is crucial to success. By employing the second generation Grubbs-Hoveyda catalyst in addition to Pt02, y- 6-lactones 

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