Valerian mexican

The LDjo of an intraperitoneally administered valerian extract (9.5 1 ethanol extract) in mice is 3.3 g/kg (Rosecrans et al. 1961). The LD50 of orally administered valerian essential oil in rats is 15 g/kg (Skramlik 1959). The LD50 of orally administered Mexican valerian extract is 3.8 g/kg (Deciga-Campos et al. 2007). 

In the Ames test for mutagenicity, a tincture of Mexican valerian did not show signs of mutagenicity, although a methanol-dichloromethane extract induced mutations in S. typhimurium TAIOO, in the presence of human liver S9 fractions, at the highest concentration tested (Deciga-Campos et al. 2007). 

Messrs. Schimmel Co. have distilled a parcel of Mexican root which was probably Valeriana Mexicana, known locally as cuittapatti. The oil had a disagreeable odour of valerianic acid its specific gravity was 949, and it was optically inactive. It appears to consist almost entirely of hydrated valerianic acid. 

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