Propofol Metoclopramide

Other prophylactic antiemetic agents include clonidine, promethazine, hyoscine, propofol, and metoclopramide. However, the data on these drugs are either insufficient or non-existent. 

Ondansetron, tramadol, and metoclopramide were less effective than lidocaine in preventing pain on injection (29-31). Ondansetron and tramadol have been compared in patients being given propofol in a randomized, doubleblind study in 100 patients (32). Tramadol 50 mg... 

Propofol in subhypnotic doses is a potent antiemetic. In a double-blind, randomized study, a small dose of propofol (0.5 mg/kg) was compared with droperidol (20 micro-grams/kg) or metoclopramide (0.2 mg/kg) given at the completion of surgery performed in 90 patients under standard anesthesia with thiopental, fentanyl, and sevo-flurane (59). Follow-up was to 24 hours. The incidence of emesis at 24 hours was significantly lower in those who received propofol (10 versus 33% and 40% for droperidol and metoclopramide respectively). 

Mok MS, Pang WW, Hwang MH. The analgesic effect of tramadol, metoclopramide, meperidine and hdocaine in amehorating propofol injection pain a comparative study. J Anaesthesiol Chn Pharmacol 1999 15 37 2. 

Fujii Y, Tanaka H, Kobayashi N. Prevention of postoperative nausea and vomiting with antiemetics in patients undergoing middle ear surgery comparison of a small dose of propofol with droperidol or metoclopramide. Arch Otolaryngol Head Neck Surg 2001 127(l) 25-8. 

Also analyzed acebutolol, acepromazine, acetaminophen, acetazolamide, acetophenazine, albuterol, amitriptyline, amobarbital, amoxapine, antipsrrine, atenolol, atropine, azata-dine, baclofen, benzocaine, bromocriptine, brompheniramine, brotizolam, bupivacaine, buspirone, butabarbital, butalbital, caffeine, carbamazepine, cetirizine, chlorqyclizine, chlordiazepoxide, chlormezanone, chloroquine, chlorpheniramine, chlorpromazine, chlorpropamide, chlorprothixene, chlorthalidone, chlorzoxazone, cimetidine, cisapride, clomipramine, clonazepam, clonidine, clozapine, cocaine, codeine, colchicine, qyclizine, (yclo-benzaprine, dantrolene, desipramine, diazepam, diclofenac, diflunisal, diltiazem, diphenhydramine, diphenidol, dipheno late, dipyridamole, disopyramide, dobutamine, doxapram, doxepin, droperidol, encainide, ethidium bromide, ethopropazine, fenoprofen, fentanyl, flavoxate, fluoxetine, fluphenazine, flurazepam, flurbiprofen, fluvoxamine, fii-rosemide, glutethimide, glyburide, guaifenesin, haloperidol, homatropine, hydralazine, hydrochlorothiazide, hydrocodone, hydromorphone, hydro g chloroquine, hydroxyzine, ibuprofen, imipramine, indomethacin, ketoconazole, ketoprofen, ketorolac, labetalol, le-vorphanol, lidocaine, loratadine, lorazepam, lovastatin, loxapine, mazindol, mefenamic acid, meperidine, mephenytoin, mepivacaine, mesoridazine, metaproterenol, methadone, methdilazine, methocarbamol, methotrexate, methotrimeprazine, methoxamine, methyl-dopa, methylphenidate, metoclopramide, metolazone, metoprolol, metronidazole, midazolam, moclobemide, morphine, nadolol, nalbuphine, naloxone, naphazoline, naproxen, nifedipine, nizatidine, norepinephrine, nortriptyline, oxazepam, oxycodone, oxymetazo-line, paroxetine, pemoline, pentazocine, pentobarbital, pentoxifylline, perphenazine, pheniramine, phenobarbital, phenol, phenolphthalein, phentolamine, phenylbutazone, phenyltoloxamine, phenytoin, pimozide, pindolol, piroxicam, pramoxine, prazepam, prazosin, probenecid, procainamide, procaine, prochlorperazine, procyclidine, promazine, promethazine, propafenone, propantheline, propiomazine, propofol, propranolol, protriptyline, quazepam, quinidine, quinine, racemethorphan, ranitidine, remoxipride, risperidone, salicylic acid, scopolamine, secobarbital, sertraline, sotalol, spironolactone, sulfinpyrazone, sulindac, temazepam, terbutaline, terfenadine, tetracaine, theophylline, thiethyl-perazine, thiopental, thioridazine, thiothixene, timolol, tocainide, tolbutamide, tolmetin, trazodone, triamterene, triazolam, trifluoperazine, triflupromazine, trimeprazine, trimethoprim, trimipramine, verapamil, warfarin, xylometazoline, yohimbine, zopiclone... 

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