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9-Methylpteroylglutamic acid

Amethopterin (Methotrexate, 4-amino-4-deoxy-Ar -methyIpteroyl-L-glutamic acid) [59-05-2] M 454.4, m 185-204°(dec), [a]p°+19° (c 2, 0.1N aq NaOH). Commonest impurities are 10-methyl pteroylglutamic acid, 4-amino-10-methylpteroylglutamic acid, aminopterin and pteroylglutamic acid. Purified by chromatography on Dowex-1 acetate, followed by filtration through a mixture of cellulose and... [Pg.463]

METHYLPTEROYLGLUTAMIC ACID see MDV500 4-AMINO-4-DEOXYPTEROYLGLUTAMATE see AMG750... [Pg.1506]

AMINO-5-NITROTHIAZOLE see ALQOOO AMINONITROTHIAZOLUM see ALQOOO 2-AMINO-4-NITROTOLUENE see NMP500 AMINONUCLEOSIDE see ALQ625 AMINONUCLEOSIDE PUROiMYCIN see ALQ625 4-AMINO-N> -METHYLPTEROYLGLUTAMIC ACID see MDV500... [Pg.1509]

Methotrexate (4-amino-10-methylpteroylglutamic acid) was one of the first folate antagonists to be used clinically and it has now heen in use for more than 30 years. It is useful for the treatment of a number of malignancies and... [Pg.239]

C Agent keyword > 4-Amino-lO-methylpteroylglutamic acid (Methotrexate)... [Pg.283]

See other pages where 9-Methylpteroylglutamic acid is mentioned: [Pg.511]    [Pg.463]    [Pg.680]    [Pg.887]    [Pg.511]    [Pg.146]    [Pg.437]    [Pg.376]   


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4-Amino-9-methylpteroylglutamic acid

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