4- methylhexan-2-amine

Case Vignette 4-Methylhexan-2-amine The great advantage of analytical procedures such as Screening I, II, and methods having evolved from these is the general and comprehensive nature. This allowed for... 

Figure 6.2 Structures of two banned stimulants 4-methylhexan-2-amine (1) and tua-...

Figure 6.3 Extracted ion chromatogram (top) of a urine sample tested positive for the two stereoisomers of 4-methylhexan-2-amine as Schiff-base derivatives using benzal-dehyde (benzylidene-(l,3-dimethylpentyl)-amine) with corresponding El mass spectrum (bottom, mol wt = 203).

A rather complex mixture of seven alcohols can be detected (besides alkenes and nitrites). The product ratio of the alcohols (normalized to 100 in Table 7-3) is dependent on the initial concentration of the amine 7.74, on the nitrosating reagent and on the mineral acid used. The product ratio in HCIO4, to a lesser extent also in HCl, is dependent on the concentration of the amine, and is obviously also influenced by the cmc. The influence of micelles can be seen in the yields for 7.75, i. e., the product of straightforward substitution, and also in the configuration of the compounds formed by a 1,2-hydride shift, 3-methylhexan-3-ol (7.76) and... 

Nitriles are common nitrogen-containing compounds. In Chapter 11 (Section 11.3.6), cyanide ion reacted as a nucleophile in an Sn2 reaction with alkyl halides to give a nitrile. When 2-bromohexane (22) is treated with NaCN in DMF, the product is 2-cyanohexane, 23. Reduction of this nitrile with LiAlH4 gives a primary amine, in this case l-amino-2-methylhexane 24. 

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