2-Methylferrocene carboxylic acid

Also, reaction site transfer observed with benzene was found not to occur with ferrocene. For example, ferrocenylmethyllithium reacted with formaldehyde to give /S-ferrocenylethanol, not 2-methylolmethylferrocene. With CO2, ferrocenylacetic acid was formed rather than 2-methylferrocene-carboxylic acid 291). This passivity may also be associated with the fact that ferrocene, a non-alternant aromatic system, cannot transfer the T-effect. 

Kunitake and coworkers have explored molecularly imprinted ultrathin titanium dioxide films. Employing a procedure of sequential chemisorption and activation onto quartz crystal microbalance (QCM) resonators, they have been able to produce stable films selective for azobenzene carboxylic acids [26] and protected amino acids [27]. In collaboration with Willner and co-workers, they have also used their synthesis techniques to functionalize ion-sensitive field-effect transistors (ISFET) with imprinted Ti02 films [28[. The resulting sensors displayed impressive selectivity in distinguishing two chloroaromatic acids. Additionally, Willner and coworkers [29] have used similar ISFET devices to generate enantioselective and enantiospecific sensors for 2-methylferrocene carboxylic acid, 2-phenylbutanoic acid, and 2-propanoic acid. 

Methylferrocene-l-carboxylic acid, X9.10 2-Methylferrocene-l-carboxylic acid, X9.8... 

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