Methylenation trimethylsilyldiazomethane

The concentration of trimethylsilyldiazo-methane in hexane can be determined by adding 91mg (0.5mmol) of dibenzyl (see [103-29-7], Aromatic compounds) in 1ml of the hexane solution containing it, and measuring the H NMR. The concentration of the azo-silane (x mmol/ml) is calculated from the formula x = 2a b, where a is the integral value (mm) of the methine proton (5 2.58) of trimethylsilyldiazomethane, and b is the integral value (mm) of the methylene protons (5 2.99) of dibenzyl. [Shioiri Aoyama Org Synth Coll Vol Vin 612 1993, Mori et al. Chem Pharm Bull Jpn 30 3380 1982],... 

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