Methylbutanedioic acid

It is important to note that the measured optical purity (P) is not necessarily linearly related to the true enantiomeric purity (ee) when nonideal conditions prevail, e.g., when the enantiomers interact between themselves. Thus, the optical purity may markedly deviate from the true enanliomeric purity if the enantiomers undergo molecular self-association51. The oligomers formed in solution display their individual optical rotation and, depending on their concentration, contribute in a specific way to the overall optical rotation. The nonequivalence between the optical and enantiomeric purities has been experimentally demonstrated for 2-ethyl-2-methylbutanedioic acid in dichloromethane (Figure 4)51. 

Methyl-1,3-butadiene, AELO Methylbutanedioic acid, AE55... 

C5H9I 1 -iodo-trans-2-pentene 66688-56-0 411.10 35.374 2 5249 C5H9N04 (R)-(-)-2-amino-2-methylbutanedioic acid 14603-76-0 504.93 44.358 2... 

Citramalic Acid. 2-Hydroxy-2-methylbutanedioic acid 2-methylmalic acid 2-hydroxy-2-methylsuccinic acid a-hydroxypyrotartaric acid trnns-methylbutanedioic add. CjHjO., mol wt 148.11. C 40.54%. H 5.44%. O 54.01%. Enzymatic synthesis Barker. Blair, Biochem. Prepns, 9, 21 (1962). Chemical synthesis Barker, ibid. 25 J. B. Wilkes, R. G. Wall. J. Org. Chem. 45, 247 (1980). Stereoselective synthesis E. G. J. Staring el al. ReC. Trav. Chim. 105, 374 (1986). 

Rocellic acid (5)-2-dodecyl-3-methylbutanedioic acid (5)-2-dodecyl-3-methylsuccinic acid, a branched chain dicarboxylic acid found in lichens. M.p. 132 °C, [a]D + 17.4° (ethanol). R.a. is biosynthesized from itaconic acid. 

Wilkes JB, Wall RG (1980) Reaction of dinitrogen tetraoxide with hydrophilic olefins synthesis of citric acid and 2-hydroxy-2-methylbutanedioic acids. J Org Chem 45 247-250 Saigsyan MS, Mkrtumyan SA, Gevorkyan AA (1989) Citric acid synthesis. Armyanskii Khim Zh 42 496-505... 

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