4-Methyl fentanyl structure

Figure 7.3 The chemical structure of fentanyl and its illegal analogues alpha-methyl-fentanyl and 3-methyl-fentanyl are shown here. Fentanyl was originally designed and marketed as an anesthetic, as it is 100 times stronger than morphine.

Figure 15.5. Structures of some "designer drugs" of abuse. Compare the structure of alpha-methyl fentanyl with that of fentanyl, MMP+ with that of pethidine, and ecstasy with that of methamphetamine.

Fig. 8.1 Comparison of the structures of morphine and some important synthetic opioid analgesics. While clear similarities in stmctnre are not always obvious, both morphine and meperidine have a phenylpipeiidine structure and a phenylpropylamine grouping, highlighted here as a sequence of three carbons hiiked to the aromatic ring via the central C13 carbon in morphine and C4 in meperidine and terminating in an Ai-methyl gronp. Fentanyl, alfentaml, remi-fentanil, and sufentanil contain a 4-anihdophenylpiperidine and a 4-anihdophenylpropylamine (highlighted) structure.

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