3- Methoxy-1,2,4-benzotriazine 1-oxide

Substitution of chlorine in 3-chloro-l,2,4-benzotiiazine 1-oxide 49 by treatment with NaCN in methanol affords 3-methoxy-l,2,4-benzotriazine 1-oxide 52 (77GEP2538179). 

The most used reaction of A -aminopyrazoles is their oxidation to 1,2,3-triazines <93LA367>. The mechanism of this reaction has been studied by Boulton <86JCS(P1)1249> using N labeling on the amino group one of the examples described is the rearrangement of l-amino-3-methoxyindazole into 4-methoxy-1,2,3-benzotriazine,... 

Substituted 1,2,3-benzotriazines 5 (R1 = Me, Ph, OMe) formed the 2-oxides 6 on V-oxidation with peroxycarboxylic acids.234 The structure was proven by 15N NMR spectroscopy. 3-Subsli-tuted l,2,3-bcnzotriazin-4(3/f)-onc 1-oxides 8 were formed on peracid oxidation of 3-alkyl- and 3-methoxy-l,2,3-benzotriazin-4(3//)-ones 7.271... 

---