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Methotrexate structure-based design

Figure 7.16 Dihydrofolate reductase inhibitors methotrexate and Compound 7, (El-Hamamsy, M.H.R.L et al. Structure-based design, synthesis and preliminary evaluation of selective inhibitors of dihydrofolate reductase from Mycobacterium tuberculosis. Bioorg. Med. Chem. 2007, 15, 4552-4576.), neuraminidase inhibitor Relenza (zanamivir), and CCR5 blocker apiaviroc. Figure 7.16 Dihydrofolate reductase inhibitors methotrexate and Compound 7, (El-Hamamsy, M.H.R.L et al. Structure-based design, synthesis and preliminary evaluation of selective inhibitors of dihydrofolate reductase from Mycobacterium tuberculosis. Bioorg. Med. Chem. 2007, 15, 4552-4576.), neuraminidase inhibitor Relenza (zanamivir), and CCR5 blocker apiaviroc.
See other pages where Methotrexate structure-based design is mentioned: [Pg.287]    [Pg.244]    [Pg.116]    [Pg.25]    [Pg.343]    [Pg.964]    [Pg.343]    [Pg.26]    [Pg.695]    [Pg.299]    [Pg.61]    [Pg.23]   
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Design Bases

Design structures

Methotrexate

Methotrexate, structure

Structure based design

Structure designable

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