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Methotrexate inhibitory activity

Account for the ability offluorouracil to act as a suicide inhibitor. Describe the inhibitory mechanism of methotrexate and aminopterin. Explain how these three compounds interfere with the growth of cancer cells. List the mechanisms by which a cell could become resistant to methotrexate. Explain the antibiotic activity of trimethoprim. [Pg.445]


See other pages where Methotrexate inhibitory activity is mentioned: [Pg.365]    [Pg.69]    [Pg.76]    [Pg.303]    [Pg.353]    [Pg.453]    [Pg.140]    [Pg.88]    [Pg.44]    [Pg.257]    [Pg.1171]    [Pg.1016]    [Pg.1291]    [Pg.1697]    [Pg.727]    [Pg.539]    [Pg.1697]    [Pg.304]    [Pg.207]    [Pg.438]    [Pg.130]    [Pg.375]    [Pg.352]    [Pg.375]    [Pg.290]    [Pg.515]    [Pg.314]   
See also in sourсe #XX -- [ Pg.127 ]




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Inhibitory activity

Methotrexate

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