Methodology of organic synthesis

E. J. Corey (Harvard) development of the theory and methodology of organic synthesis. 

Hydrogenolysis of Cyclic Nitronates Since hydrogenolysis of substituted cyclic nitronates afford polyfunctional derivatives, this reaction is of interest for the development of a methodology of organic synthesis. However, this process has been poorly studied. 

Selective Reduction of the O-N-O Fragment in Cyclic and Bicyclic Fused Nitroso Acetals From the point of development of methodology of organic synthesis, selective reduction of the nitroso acetal fragment and associated processes are the most important reactions of nitroso acetals (also see Scheme 3.154). 

Application of simple sugars as starting materials for the preparation of optically pure complex products represents nowadays the classic methodology of organic synthesis it is covered by many comprehensive reviews, cited here only in references.88 These references provide the precise state-of-art in the synthesis of aza sugars, carbasugars and other derivatives. 

E. Steckhan, P. Bmngs, A. Zietlow, et al. in Modern Methodology of Organic Synthesis, Proceedings of the 1991 International Symposium on Organic Reactions, Kyoto (Ed. S. Shono), Kodansha, Tokyo, 1992, pp. 323-337. 

In 1990, the Nobel Prize in Chemistry was awarded to E. J. Corey for the development of the theory and methodology of organic synthesis . As was summarized in Corey s Nobel lecture, the essence of his research was in advancing the level of synthetic science by an approach consisting of three integral components the development of more general and powerful ways of... 

The Nobd Prize in Chemistry 1990. Professor E.J. Corey for his development of the theory and methodology of organic synthesis . http //www.marinespedes.org/index.php Worms, world Register of Marine Species. http //dcb-carot.unibe.ch/homepages /daniel /XENlintro.htm Xenicanes. Site dedicated to this particular family of diterpenes (xenicanes). 

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