Methanol esters

Other metals capable of electrophilic substitution of C-H bonds are salts of palladium and, environmentally unattractive, mercury. Methane conversion to methanol esters have been reported for both of them [29], Electrophilic attack at arenes followed by C-H activation is more facile, for all three metals. The method for making mercury-aryl involves reaction of mercury diacetate and arenes at high temperatures and long reaction times to give aryl-mercury(II) acetate as the product it was described as an electrophilic aromatic substitution rather than a C-H activation [30],... 

Oxyphencyclimine Oxyphencylimine, the l,4,5,6-tetrahydro-l-methyl-2-pyrimidinyl-methanolic ester of a-phenylcyclohexaneglycoUc acid (14.1.37), is synthesized by the... 

The compounds represented in this facsimile were as follows Nl, neutral lipids (cholesterol, triacylglycerol) PE, phosphatidylethanolamine PS, phos-phatidylserine PI, phosphatidylinositol PC, phosphatidylcholine Sph, sphingomyelin X, gangliosides, polyphosphoinositides, lysophosphatidic acids. The chromatography was done on silica gel G plates with chloroform-methanol-ester (65 35 31, v/v) as the solvent. 

The transesterification reactions were performed at 70°C with molar ratio of methanol / ester function / catalyst = 2.3/1 / 0.02 and at atmospheric pressure. The rates were monitored by H NMR.23 The results are given in Table 1. 

In an important development, Periana made Shilov-hke chemistry more practically useful with a series of methane conversion catalysts. The first such system involved Hg(n) salts in H2SO4 at 180°, the latter being both a solvent and a mild reoxidant (equation 3). Methane was converted to the methanol ester, methyl bisulfate, MeOSOsH, in which the -OSO3H provides a powerful deactivating group to... 

The removal of water from the reaction mixture requires application of much greater levels of energy consumption and separation technology. Re-esterification of the methanol ester with glycol makes it easier to separate the methanol. 

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