Chest pain metamfetamine

A 31-year-old man developed generalized discomfort after injecting four doses of amfetamine and metamfetamine over 48 hours, but no chest pain or tightness or shortness of breath. Electrocardiography showed inverted T-waves and left bundle branch block. Echocardiography showed reduced anterior wall motion. 

A 28-year-old healthy woman had left-sided pleuritic chest pain for 18 hours, having taken one tablet of ecstasy and one tablet of speed (metamfetamine hydrochloride) 4 hours earlier. There was surgical emphysema in her neck. On auscultation there was a crunching cardiac systolic sound. Chest X-ray showed pneumopericardium and pneumomediastinum. She was given analgesics and monitored. The chest pain subsided after 4 days. 

---