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Metalation of a-picoline by phenyl lithium

Metalation of a-picoline by phenyl lithium, 23, 84 Metal bath, 20, 48... [Pg.57]

The reactivity of the 1-methyl group and of corresponding positions (i.e., a-carbon atoms) in other l-alkyl-j8-carbolines, analogous to that in a-picoline, quinaldine, and isoquinaldine, is due to the acidity of this center. Deprotonation yields a resonance-stabilized anion (288) which reacts readily with electrophilic reagents. Metallation with phenyl-lithium of the 1-methyl group of a l-methyl-j8-carboline derivative in which the indole nitrogen is protected, first described by Woodward... [Pg.153]

See other pages where Metalation of a-picoline by phenyl lithium is mentioned: [Pg.29]    [Pg.327]   
See also in sourсe #XX -- [ Pg.23 , Pg.84 ]

See also in sourсe #XX -- [ Pg.23 , Pg.84 ]

See also in sourсe #XX -- [ Pg.23 , Pg.84 ]

See also in sourсe #XX -- [ Pg.23 , Pg.84 ]

See also in sourсe #XX -- [ Pg.23 , Pg.29 , Pg.44 , Pg.84 ]

See also in sourсe #XX -- [ Pg.23 , Pg.84 ]

See also in sourсe #XX -- [ Pg.23 , Pg.84 ]

See also in sourсe #XX -- [ Pg.23 , Pg.84 ]



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4-Picoline

A-PHENYL

By Lithium

Lithium metal

Metal phenyls

Metallic lithium

Metals lithium metal

Phenyl-lithium

Picolin

Picolinates

Picoline phenylation

Picolines

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