Metal detectors choosing

The Scatchard formalism can of course be applied to the binding of any small molecule to any biomacromolecule, such as the binding of a substrate or inhibitor to an enzyme, or the binding of a metal ion to an apoprotein. In receptor research, the determination of Kd typically requires labeling of the substrate by radioactivity or by fluorescence. However, we might just as well choose paramagnetism as the label, and this then makes the EPR spectrometer the detector for the determination of binding equilibria. The Scatchard plot in Equation 13.4 has two experimental observables [L] and [RL], and so we must find ways to determine these quantities from EPR spectra. 

In choosing the correct detectors, other particular facts should also be considered. Whereas most ordnance is ferrous, fuses may be nonferrous and are usually buried separately from the projectile bodies and may be in large and dangerous quantities. Some explosives such as dynamite or C-3 and C-4 may not be in metallic containers, thus the nonferrous detonators may be the only clue to their location. Also, some chemical agent containers are nonferrous. Chemical weapon test sites may have the unique problem of arsenic, magnesium, and other metals in the soil. Ranges may have copper and beryllium in the soil. The effects of such contamination or natural soil conditions on the detection equipment should be carefully considered. 

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