Metal-Catalyzed MCRs Involving NHCs as Ligands

2 Metal-Catalyzed MCRs Involving NHCs as Ligands 

It is possible to say without any doubt that the popularity of NHC ligands in the design of homogeneous catalysis is 

SCHEME SAS Proposed mechanism for NHC-catalyzed 3CR of alkynyl aldehydes with oxindoles. 

NHC-based catalysts feature robust carbon-metal bonds that provide high thermal stability, low dissociation rates, and, consequently, better resistance against oxidation or 

The remarkable catalytic performances shown by M-NHC complexes (compatibility with many reagents, reaction conditions, other catalysts, and activation modes) have allowed their increasing application in MCRs. In this section, the most representative and recent outcomes developed in this field are presented. With the aim of facilitating the reading, this section has been divided according to the different transition metals used and the specific MCR described. 

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