Metabolism of Environmental Chemicals Biotransformation

Subsequent to the entry of an environmental chemical into a mammalian organism, chemical reactions occur within the body to alter the structure of the chemical. This metabolic conversion process is known as biotransformation and occurs in any of several tissues and organs such as the intestine, lung, kidney, skin, and liver. 

By far the largest number of these chemical reactions are carried out in the liver. The liver metabolizes not only drugs but also most of the other foreign 

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