Metabolism bioenergetics

Dynamic and quantitative aspects of metabolism bioenergetics and enzyme kinetics... 

The ways in which energy in the form of ATP is produced and utilized constitute bioenergetics, and will be discussed in greater detail at the end of this chapter. However, before turning to a selection of metabolic pathways, we outline some fundamental notions concerning redox reactions followed by a brief description of the central role of ATP in metabolism as an acceptor and donor of phosphoryl groups, and finally a summary of the types of reactions that we will encounter as we wend our way along a sample of some of the pathways of intermediary metabolism. 

Introductions to enzyme kinetics and bioenergetics are given with explanations of key terms such as Km and Vmax coenzymes, cofactors and inhibitors typical metabolic reactions free energy exergonic and endergonic reactions, catabolism and anabolism. 

Thus far, our discussion has considered the chemical changes which constitute metabolism. We must now introduce some fundamental ideas of bioenergetics. Further details can be found in Chapter 2. 

All molecules have an amount of energy determined mainly by their chemical structure. Metabolism involves chemical change. Inevitably therefore, energy changes always accompany the chemical changes which occur in metabolism. Our understanding of bioenergetics arises from physics and the laws of thermodynamics. 

Gest H. 1999. Bioenergetic and metabolic process patterns in anoxyphototrophs. In Peschek G A, Loffelhardt W, Scmetterer G, editors. The phototrophic prokaryotes. New York Kluwer Academic/Plenum. P 11-9. 

Becker, W.M. (1977) Energy and the Living Cell An Introduction to Bioenergetics, J. B. Ldppincott Company, Philadelphia A clear introductory account of cellular metabolism, in terms of... 

UNIT II Intermediary Metabolism Chapter 6 Bioenergetics and Oxidative Phosphorylation 69 Chapter 7 Introduction to Carbohydrates 83 Chapter 8 Glycolysis 89 Chapter 9 Tricarboxylic Acid Cycle 107 Chapter 10 Gluconeogenesis 115 Chapter 11 Glycogen Metabolism 123... 

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