Metabolism autonomic control

CFS patients and is related to autonomic dysfunction. In a separate rat study, Giannesini et al. used citrulline malate (CM) to treat asthenia and found that the supplementation prevented the basal PCr/ATP ratio reduction and normalized the pHi time-course during muscular activ-ity. They conclude that CM supplementation corrects the impaired control of oxidative function and has protective effect on basal energy metabolism. The data from either human or animal studies provide a potential approach to therapy. 

Biologically, the autonomic nervous system controls many physiological functions, including respiration, circulation, metabolism, digestion, secretions, and body tempera-ture. The sympathetic and parasympathetic systems are the two major divisions of the autonomic nervous system. In general, they are antagonistic (one stimulates while the other... 

The usual e qilanatlon of this phenomenon is that organisms during their historical development have formed autonomous oscillator systems transmitted genetically, parallel in their action with natural periods, and capable of adjustment. These systems are somehow connected with the controlling systems of metabolism, i.e., with the chromosomes. 

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