Metabolism, and Chemical Detection Methods of Pectenotoxins

Owing to the difficulties in distinguishing between DSP toxins and pectenotoxins by the traditional mouse bioassay, several chemical analyses have been developed. These methods are based on liquid chromatography (LC) with detection by ultraviolet (UV) absorption [4-7,20,25,26], fluorescence (FL) [6,7,9-11,25-27], andmass spectrometry (MS) [5-8,10-21,23,24,28-36]. Amajor drawback of these LC techniques is the lack of analytical standards. In the present chapter, chemistry, metabolism, and chemical detection methods of pectenotoxins are described. Pharmacology and toxicology of pectenotoxins will be discussed in other chapters. 

Seafood and Freshwater Toxins Pharmacology, Physiology, and Detection 

Chemical and Physical Properties of Pectenotoxins Reported Previously 

Name Molecular Formula MWt Melting Point (°C) UV Z max (nm) [al D IR Band (cmb References 

Treatment of 7R-pectenotoxins under acidic condition such as acetonitrile/water (7 3, v/v) with 

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Chemistry, Metabolism, and Chemical Detection Methods of Pectenotoxins... 

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